Korean J Obstet Gynecol.  2011 Aug;54(8):464-467. 10.5468/KJOG.2011.54.8.464.

An orbital hemangioendothelioma of fetus detected by prenatal ultrasonography

• Bae JG
• Lim SY
• Rhee JH
• Kim JI
• Park JC

• KMID: 2274068
• DOI: http://doi.org/10.5468/KJOG.2011.54.8.464

Abstract

Most orbital tumors of infants include retinoblastoma, dermoid cyst (teratoma), optic nerve glioma and nevus, and hemangioendothelioma is found in rare cases. Hemangioendothelioma, the tumor of intermediate malignancy between angiosarcoma and hemangioma, is commonly recognized in soft tissue of extremities, skin, lung and liver with symptoms of ulceration and hepatomegaly in neonates and infants. However it seldom localizes in the orbit. Although there have been two case reports of orbital hemangioendothelioma in neonate and adult in Korea, there was no case report of prenatally diagnosed orbital hemangioendothelioma in fetus. We found hemangioma-like orbital tumor in a fetus at 36 weeks of gestation by prenatal ultrasonography and confirmed hemangioendothelioma by microscopic examination after birth. This is the first case of orbital hemangioendothelioma in fetus.

Keyword

Orbit; Hemangioendothelioma; Ultrasonography, prenatal

MeSH Terms

Adult
Dermoid Cyst
Extremities
Fetus
Hemangioendothelioma
Hemangioma
Hemangiosarcoma
Hepatomegaly
Humans
Infant
Infant, Newborn
Korea
Liver
Lung
Nevus
Optic Nerve Glioma
Orbit
Parturition
Pregnancy
Retinoblastoma
Skin
Ulcer
Ultrasonography, Prenatal

Figure

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  Fig. 1 At 36 weeks, ultrasonography reveals 6.5 × 4.8 cm sized mass on left frontal area of fetal head.

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  Fig. 2 3D-ultrasonography shows heterogenous mass on left orbital area of a 36 weeks old fetus.

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  Fig. 3 Fetal magnetic resonance image shows a relatively well-definded, huge, heterog-enous, solid mass involving the left orbit, infratemporal fossa, epidural space of left frontal and temporal lobe of a fetus, measuring 82×62×75 mm (arrow). The mass is highly vascular, internal hemorrhagic and tiny calcified foci. Several large draining vessels are noted.

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  Fig. 4 After birth we defined huge orbital mass occupying left orbit and left frontotemporal area of a newborn infant.

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