Korean J Obstet Gynecol.  2010 Aug;53(8):737-741. 10.5468/kjog.2010.53.8.737.

A case of borderline clear cell fibroadenoma

Affiliations
  • 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. pnhkhr@snu.ac.kr
  • 2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Clear cell tumor of borderline malignancy has been reported to account for 5 to 8% of all clear cell neoplasms, and <1% of borderline malignancies of the ovary. Borderline clear cell fibroadenoma with or without microinvasion mostly occurs in women with middle age, and the presenting symptoms associated with this tumor are non-specific. The clinico-pathologic features of borderline clear cell fibroadenoma are not well known because of its rarity. Furthermore, there is no consensus for treating the disease. Thus, we report a case of borderline clear cell fibroadenoma presenting as ovarian fibroadenoma with a review of literature.

Keyword

Borderline malignancy; Clear cell tumor; Fibroadenoma

MeSH Terms

Consensus
Female
Fibroadenoma
Humans
Middle Aged
Naphazoline
Ovary
Naphazoline

Figure

  • Fig. 1 (A) Trans-abdominal ultrasonogram showed over 12 cm sized multi-septated solid cyst in pelvic cavity. (B) Magnetic resonance imaging showed 12 cm sized, well-marginated, multi-septated, huge mass including solid portion.

  • Fig. 2 (A) The cut surface of ovarian cystic mass was solid and variable sized cysts in appearance and had minute cysts embedded in a firm stroma. (B) Clear cell adenofibroma of borderline malignancy showing widely spaced to focally crowded glands in abundant stromal component (H&E stain, ×100).


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