Korean J Obstet Gynecol.  2008 Oct;51(10):1128-1136.

Prevalence and distribution of single and multiple HPV infections in cervical cancer and precancerous lesion from Daegu and Gyeongbuk province

Affiliations
  • 1Department of Obstetrics and Gynecology, School of Medicine, Catholic University of Daegu, Daegu, Korea. sbko@cu.ac.kr

Abstract


OBJECTIVE
We analysed subtype of HPV infection in cervical cancer and precancerous lesion among women who lived in Daegu and Gyeongbuk province.
METHODS
We recruited total of 441 women diagnosed with cytologically abnormal cervical samples between Dec. 2004 and Dec. 2006. We investigated the distribution of HPV subtype and multiple infection according to cervical lesion and age.
RESULTS
The most prevalent HPV subtypes in cervical cancer and precancerous lesion were HPV 16, 58, 18, 31, 56 in ASCUS, HPV 16, 58, 52, 66, 18 in LSIL, HPV 16, 58, 33, 52, 18 in HSIL, HPV 16, 58, 33, 52, 53 in IC each other. IC was less multiple infection than ASCUS, LSIL, HSIL. There was strong correlation between the incidence of multiple HPV infection and cervical lesion in young women (<25 years).
CONCLUSION
The types of HPV 16, 58, 52, 18 were common in cervical cancer and precancerous lesion from Daegu and Gyeongbuk province. Multiple infections were more common in women under 25 years of age than above age and precancerous lesion.

Keyword

Human papillomavirus; Cytologically abnormal cervical samples
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