Korean J Obstet Gynecol.  2003 May;46(5):991-997.

FDG-PET Scan in Patients with Pelvic Recurrence of Cervical Cancer

Affiliations
  • 1N-C-C, Research Institute and Hospital, Goyang, Korea.

Abstract


OBJECTIVE
The purpose of this study was to investigate the clinical feasibility of FDG-PET scan in selection of patients with pelvic recurrence of cervical cancer for surgical treatment.
METHODS
From Jun. 2001 to Oct. 2002, whole body FDG-PET scan findings were compared with findings of CT, MRI, and pathologic reports in 24 patients with pelvic recurrence of cervical cancer. PET scan was obtained with a GE Advance PET scanner, beginning at 60 minutes after injection of 370-555 MBq (10- 15 mCi) of 18F FDG. Regional scan was also obtained if needed. Uptake exceeding 2.5 SUV was determined as a positive finding.
RESULTS
Among these 24 patients, 10 patients had metastatic lesions at pelvic lymphnodes (4), para- aortic lymphnodes (3), mediastinal lympnnodes (1), lung (4), and bone (1). Among 14 patients with no metastasis, 10 patients underwent surgical treatment but the operations were abandoned in 2 patients due to lymphnodes metastasis and pelvic peritoneal spreads that confused as normal FDG uptake of the intestines pre- operatively. Among 8 patients whom the operation was completed, 3 patients received pelvic exenteration, 2 patients received CORT, and 3 patients received LEER.
CONCLUSION
FDG-PET is clinically feasible in selection of patients with pelvic recurrence of cervical cancer for surgical treatment.

Keyword

Cervical cancer; PET; Pelvic exenteration

MeSH Terms

Humans
Intestines
Lung
Magnetic Resonance Imaging
Neoplasm Metastasis
Pelvic Exenteration
Positron-Emission Tomography
Recurrence*
Uterine Cervical Neoplasms*
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