Korean J Orthod.  1995 Apr;25(2):153-163.

Comparative study on the horizotal measurements of skeletal Class III malocclusion using the ROC analysis

  • 1Department of Orthodontics, College of Dentistry, Seoul National University, Korea.


In this study, Receiver Operating Characteristic(ROC) analysis was used to evaluate the ability of cephalometric measurements to identify patients with Class III malocclusions. ROC analysis is the method for determining the validity of a diagnostic measure and for evaluating the relative value of diagnostic tests. The sample consisted of 496 patients with malocclusion. Class III malocclusion is defined as the dental relationship for which The mesiobuccal groove of the lower first molar is deviated mesially from the mesiobuccal cusp of the upper first molar. Of the total sample of 496 patients, 245 had Class III malocclusions. 16 cephalometric measurements were selected, each of which was treated as a diagnostic test. The ROC curves were generated for each cephalometric measurement with intervals of 1.0degrees for angular measurements, 1.0mm for linear measurements. The area under the ROC curves was measured for direct comparison among different diagnostic tests. The results were as follows: 1. The "Wits" appraisal was found to be a better diagnostic criterion for the presence of Class III malocclusion than any other commonly used cephalometric measurement. 2. AB plane angle, ANB angle, App-Bpp distance. AF-BF distance, APDI, Distance of point A and Pog to N perpendicular, maxillomandibular differential had high diagnostic value. 3. Cephalometric measurements which evaluate the position of the mandible had moderate diagnostic value. 4. Cephalometric measurements related to the maxilla discriminated least between patients with and without Class III malocclusion.


ROC analysis; diagnostic value; Class III malocclusion

MeSH Terms

Diagnostic Tests, Routine
ROC Curve*
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