Korean J Obstet Gynecol.
2002 Dec;45(12):2319-2324.
Case of Adenoma Malignum of the Uterine Cervix
- Affiliations
-
- 1Department of Obstetrics and Gynecology, Kyung Hee University, College of Medicine, Seoul, Korea.
- 2Department of Anatomical Pathology, Kyung Hee University, College of Medicine, Seoul, Korea.
Abstract
- Adenoma malignum (minimal deviation adenocarcinoma) is a rare, extremely well-differentiated form of invasive cervical adenocarcinoma. The name derives from the deceptively benign epithelial cells that line the glands of this neoplasm. The presence of architectural disorder with irregular, abnormally shaped invasive glands sometimes surrounded by a desmoplastic stromal response or demonstrating vascular and perineural invasion may be the only features establishing its malignant nature. Despite its bland appearance, adenoma malignum may carry a poor prognosis. Because of its rarity, and possibly because diagnostic changes are subtle and may be missed, there are few reports. A case of adenoma malignum of the uterine cervix is presented with a brief review of the literatures.
