Asian Spine J.  2013 Sep;7(3):227-231. 10.4184/asj.2013.7.3.227.

Giant Invasive Sacral Schwannoma Showing Chromosomal Numerical Aberrations [-14,+18,+22]

• Kanamori M
• Yasuda T
• Hori T
• Suzuki K

• KMID: 2270437
• DOI: http://doi.org/10.4184/asj.2013.7.3.227

Abstract

Here, we report on a rare case of a giant invasive sacral schwannoma. The patient was a 58-year-old woman who had a 6-year history of non-specific buttock pain. Histological investigation confirmed the diagnosis of cellular schwannoma. The following numerical aberration was detected using the GTG-banding method for karyotypes: 47,XX,-14,+18,+22. Cytogenetic studies of schwannomas have indicated a complete or partial loss of chromosome 22 as the most common abnormality, but this case is cytogenetically rare because of the recurrence of trisomy 22.

Keyword

Sacrum; Neurilemmoma; Cytogenetics

MeSH Terms

Buttocks
Chromosomes, Human, Pair 22
Cytogenetics
Female
Humans
Middle Aged
Neurilemmoma
Recurrence
Sacrum
Trisomy
Chromosomes, Human, Pair 22
Trisomy