Asian Oncol Nurs.  2014 Jun;14(2):58-65. 10.5388/aon.2014.14.2.58.

Impact of Climacteric Symptoms and Fatigue on the Quality of Life in Breast Cancer Survivors: The Mediating Effect of Cognitive Dysfunction

• Kim GD

• KMID: 2269459
• DOI: http://doi.org/10.5388/aon.2014.14.2.58

Abstract

PURPOSE
The purpose of this study was to test hypothetical model of quality of life (QOL) in breast cancer survivors and to test the mediating effects of cognitive dysfunction.
METHODS
This study was conducted from December 1st, 2013 to February 28th, 2014. 164 breast cancer survivors were recruited from A, D, and Y city in Korea. The instruments used in this study were climacteric symptoms, fatigue, cognitive dysfunction, and the QOL scales. Data were analyzed using descriptive statistics, correlation, and pathway.
RESULTS
Cognitive dysfunction was directly affected by climacteric symptoms and fatigue. QOL was directly affected by fatigue, However climacteric symptoms and cognitive dysfunction did not effect on QOL directly. Impact of climacteric symptoms on QOL, mediating effect of cognitive dysfunction was not confirmed. In addition, effect of fatigue on the QOL, the mediating effect of cognitive dysfunction was not.
CONCLUSIONS
Effects of climacteric symptoms on QOL was not mediated by cognitive dysfunction, Furthermore effects of fatigue on QOL was not mediated by cognitive dysfunction.

Keyword

Breast Neoplasms; Climacteric Symptoms; Fatigue; Cognitive Dysfunction; Quality of Life

MeSH Terms

Breast Neoplasms*
Climacteric*
Fatigue*
Humans
Korea
Negotiating*
Quality of Life*
Survivors*
Weights and Measures

Figure

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  Fig. 1 Conceptual framework.

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  Fig. 2 Pathway model of climacteric symptoms, fatigue, cognitive dysfunction, and quality of life.

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