Korean J Med.
2014 Nov;87(5):619-624. 10.3904/kjm.2014.87.5.619.
Polycythemia Vera Presenting with Generalized Chorea: A Case Report and Review of the Literature
- Affiliations
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- 1Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. mlee@kuh.ac.kr
- 2Department of Neurology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- 3Department of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- KMID: 2269207
- DOI: http://doi.org/10.3904/kjm.2014.87.5.619
Abstract
- Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by erythrocytosis. Clinical symptoms can range in severity from headache and tinnitus to thrombohemorrhagic complications. Neurologic symptoms are common at the onset of polycythemia; however, chorea due to PV is a rare complication. We present the case of a 77-year-old female who was referred to our hospital because of choreic movement of the limbs, head and face. She was diagnosed with JAK2V617F mutation-positive PV. Her chorea was completely resolved by phlebotomy combined with hydroxyurea and aspirin.
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