Korean J Med.  2015 Sep;89(3):353-357. 10.3904/kjm.2015.89.3.353.

A Case of Primary Cutaneous Anaplastic Large Cell Lymphoma with Extensive Limb Disease

• Byeon JH
• Woo IS
• Lee WJ
• Kam SH
• Han CW
• Jung YH

• KMID: 2269012
• DOI: http://doi.org/10.3904/kjm.2015.89.3.353

Abstract

Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare subtype of malignant non-Hodgkin lymphoma, in which 40% of the cases show spontaneous regression without aggressive treatment. Surgery and focal radiation therapy are the primary forms of treatment for this disease; however, if pcALCL is accompanied by multifocal skin lesions, chemotherapy is also common. The prognosis for pcALCL is generally excellent, with a 5-year survival rate of 85-100%. However, pcALCL with extensive limb disease typically has a poor prognosis. Here, we present a case of pcALCL with extensive limb disease that resulted in the patient's death, despite the use of aggressive chemotherapy.

Keyword

Lymphoma; Primary cutaneous anaplastic large cell

MeSH Terms

Drug Therapy
Extremities*
Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, Primary Cutaneous Anaplastic Large Cell*
Prognosis
Skin
Survival Rate