Ann Dermatol.  2013 Aug;25(3):382-384. 10.5021/ad.2013.25.3.382.

Medallion-Like Dermal Dendrocyte Hamartoma: Differential Diagnosis with Congenital Atrophic Dermatofibrosarcoma Protuberans

• Cheon M
• Jung KE
• Kim HS
• Lee JY
• Kim HO
• Park CK
• Park YM

• KMID: 2265887
• DOI: http://doi.org/10.5021/ad.2013.25.3.382

Abstract

No abstract available.

MeSH Terms

Dermatofibrosarcoma
Diagnosis, Differential
Dermatofibrosarcoma

Figure

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  Fig. 1 A solitary, depressed, erythematous to yellowish plaque with fine wrinkles on the posterior neck. (A) Frontal view, (B) side view.

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  Fig. 2 (A) Full-thickness dermal cellular proliferation (H&E, ×40). (B) Proliferation of spindle-shaped or ovoid cells arranged focally in a storiform-like pattern (H&E, ×400). (C) Positive staining with CD34 (×400). (D) Positive staining with factor XIIIa (×400).

Reference

1. Rodríguez-Jurado R, Palacios C, Durán-McKinster C, Mercadillo P, Orozco-Covarrubias L, Saez-de-Ocariz Mdel M, et al. Medallion-like dermal dendrocyte hamartoma: a new clinically and histopathologically distinct lesion. J Am Acad Dermatol. 2004; 51:359–363.

2. Marque M, Bessis D, Pedeutour F, Viseux V, Guillot B, Fraitag-Spinner S. Medallion-like dermal dendrocyte hamartoma: the main diagnostic pitfall is congenital atrophic dermatofibrosarcoma. Br J Dermatol. 2009; 160:190–193.

3. Restano L, Fanoni D, Colonna C, Gelmetti C, Berti E. Medallion-like dermal dendrocyte hamartoma: a case misdiagnosed as neurofibroma. Pediatr Dermatol. 2010; 27:638–642.

4. Bandarchi B, Ma L, Marginean C, Hafezi S, Zubovits J, Rasty G. D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans. Mod Pathol. 2010; 23:434–438.

5. Maire G, Fraitag S, Galmiche L, Keslair F, Ebran N, Terrier-Lacombe MJ, et al. A clinical, histologic, and molecular study of 9 cases of congenital dermatofibrosarcoma protuberans. Arch Dermatol. 2007; 143:203–210.