Ann Dermatol.  2015 Feb;27(1):99-100. 10.5021/ad.2015.27.1.99.

A Case of Extramammary Paget's Disease Resistant to Photodynamic Therapy and Surgery Successfully Treated with Radiotherapy

• Park YJ
• Kim YC

• KMID: 2264849
• DOI: http://doi.org/10.5021/ad.2015.27.1.99

Abstract

No abstract available.

MeSH Terms

Paget Disease, Extramammary*
Photochemotherapy*
Radiotherapy*

Figure

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  Fig. 1 (A) Patient image at initial visit. (B) The patient revisited our clinic suspecting of recurrence. The biopsy of skin lesion did not show any tumor cells.

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  Fig. 2 Skin biopsy showing acanthotic epidermis with numerous Paget cells of large nucleus and eosinophilic cytoplasm (H&E, ×200).

Reference

1. Lee SJ, Choe YS, Jung HD, Ahn SK, Cha YC, Cho KH, et al. Korean Society for Skin Cancer and Korean Dermatopathology Research Group. A multicenter study on extramammary Paget's disease in Korea. Int J Dermatol. 2011; 50:508–515.

2. Nardelli AA, Stafinski T, Menon D. Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review. BMC Dermatol. 2011; 11:13.

3. Li Q, Gao T, Jiao B, Qi X, Long HA, Qiao H, et al. Long-term follow-up of in situ extramammary Paget's disease in Asian skin types IV/V treated with photodynamic therapy. Acta Derm Venereol. 2010; 90:159–164.

4. Dilmé-Carreras E, Iglesias-Sancho M, Márquez-Balbás G, Sola-Ortigosa J, Umbert-Millet P. Radiotherapy for extramammary Paget disease of the anogenital region. J Am Acad Dermatol. 2011; 65:192–194.