Ann Dermatol.  2015 Feb;27(1):94-96. 10.5021/ad.2015.27.1.94.

A Case of Primary Palmoplantar Kaposi Sarcoma: An Unusual Presentation

Affiliations
  • 1Department of Dermatology, Kangwon National University School of Medicine, Chuncheon, Korea.
  • 2Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
  • 3Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. kim937121@naver.com

Abstract

No abstract available.


MeSH Terms

Sarcoma, Kaposi*

Figure

  • Fig. 1 (A) Variable-sized, multiple, discrete violaceous to brownish patches on both palms. (B) Extensive indurated and hyperkeratotic plaques on both soles.

  • Fig. 2 (A) Numerous, irregular, bizarre, dilated thin-walled small vascular channels in the dermis (H&E, ×100). (B) Normal blood vessel protruding into newly formed blood vessels characteristic of the promontory sign (H&E, ×400). (C) Immunohistochemistry for human herpes virus 8 (HHV-8) showed strong nuclear staining of spindle-shaped cells (HHV-8 stain, ×200). (D) Immunohistochemical staining revealed a positive reaction to factor VIII-related antigen (factor VIII-related antigen stain, ×100). (E) Whole-body F-18 FDG PET/CT scan showed no other abnormal uptake except in both palms and both soles.


Reference

1. Radu O, Pantanowitz L. Kaposi sarcoma. Arch Pathol Lab Med. 2013; 137:289–294.
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2. Schwartz RA, Micali G, Nasca MR, Scuderi L. Kaposi sarcoma: a continuing conundrum. J Am Acad Dermatol. 2008; 59:179–206.
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3. Al Zolibani AA, Al Robaee AA. Primary palmoplantar Kaposi's sarcoma: an unusual presentation. Skinmed. 2006; 5:248–249.
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4. Naschitz JE, Lurie M. Macular palmo-plantar eruption. Eur J Intern Med. 2009; 20:e118–e119.
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5. Ozbek MR, Kutlu N. A rare case of Kaposi's sarcoma; hand localization. Handchir Mikrochir Plast Chir. 1990; 22:107–109.
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