Korean J Obstet Gynecol.
1999 Dec;42(12):2787-2791.
Pregnancy Rate Following Superovulation with Intrauterine Insemination in Infertile Patients
Abstract
OBJECTIVES
To investigate the efficiency of superovulation with intrauterine insemination (IUI) in infertile patients.
MATERIALS AND METHODS
Seventy-two cycles of superovulation with IUI in 48 infertile couples in which gonadotrophins were used for hyperstimulation were analysed retrospectively.
RESULTS
Overall clinical pregnancy rate was 33.3% per cycle and 45.8% per patient. By the infertility factor, patients with endometriosis showed the lowest pregnancy rate (10%). Cumulative pregnancy rate (CPR), obtained by life-table analysis, increased as the number of cycles increased: 25.0% for one cycle, 33.3% for two cycle, 40% for three cycle and 50% for more than four cycle.
CONCLUSIONS
Superovulation with IUI is an effective treatment modality in patients with subfecundity, and is worth while trying prior to in vitro fertilization procedure in those patients.