Korean J Obstet Gynecol.  1998 Dec;41(12):3040-3043.

Prenatal Cytogenetic Analysis of 145 Fetuses Conceived by Intracytoplasmic Sperm Injectiion ( ICSI )

• Lee SH
• Oum KB
• Lee EJ
• Yoon TK
• Cha KY
• Kwak IP
• Choi DH

Abstract

Prenatal diagnoses were performed in 145 fetuses resulting from 73 singleton and 36 twin pregnancies, all established by intracytoplasmic sperm injection (ICS: amniocentesis in 108 patients and Chorionic villus sampling in one. The prenatal cytogenetic results were obtained from pregnancies after ICSI using ejaculated spermatozoa, epididymal spermatozoa, testicular spermatozoa and after the replacement of frozen-thawed embryos derived from ICSI. The Karyotypes were normal in 138 cases (95.2%) of the prenatal diagnoses and there were 2 cases (1.4%) de novo and 5 cases (3.4%) inherited chromosomal aberrations. The two cases of de novo abnormalities were: 46, XY, t(6;7)(q21;p22) and 47, XY, +21 (trisomy 21).

Keyword

Intracytoplasmic sperm injection (ICSI); Prenatal diagnoses; Chromosomal aberrations

MeSH Terms

Amniocentesis
Chorionic Villi Sampling
Chromosome Aberrations
Cytogenetic Analysis*
Cytogenetics*
Embryonic Structures
Female
Fetus*
Humans
Karyotype
Pregnancy
Pregnancy, Twin
Prenatal Diagnosis
Sperm Injections, Intracytoplasmic*
Spermatozoa*