Korean J Obstet Gynecol.  1998 Aug;41(8):2241-2245.

A Case of Diffuse Malignant Mesothelioma of the Peritoneum

• Kim S
• Shin YS
• Seo YS
• Park YS
• Nam SL
• Seo KS

Abstract

Primary malignant mesothelioma of the peritoneum is a rare condition(annual incidence: 1~2 cases per million in the general population). A case of diffuse malignant mesothelioma of the peritoneum of a 54-year-old woman is reported. After laparotomy the patient was treated with intraperitoneal chemotherapy with cisplatin (100 mg), postoperative chemotherapy (6 cycles) with carboplatine (350 mg/m2), and cyclophosphamide (750 mg/m2). In the second-look operation, malignant mesothelioma was as minute nodules at the site of adhesion. So she had further treated with combination chemotherapy using cyclophamide (500 mg/m2) and pinorubicin (40mg/m2), and continude follow up of the CA 125 levels. The patient it still alive and the serum CA 125 level showed a close relation with the reponse to treatment (Surgery and chemotherapy). On the basis of the data from literature, we briefly review the epidemiology, diagnosis, and treatment of malignant peritoneal mesothelioma.

MeSH Terms

Carboplatin
Cisplatin
Cyclophosphamide
Diagnosis
Drug Therapy
Drug Therapy, Combination
Epidemiology
Female
Follow-Up Studies
Humans
Incidence
Laparotomy
Mesothelioma*
Middle Aged
Peritoneum*
Carboplatin
Cisplatin
Cyclophosphamide