Allergy Asthma Immunol Res.  2014 May;6(3):187-188. 10.4168/aair.2014.6.3.187.

Immunomodulating Approach to Asthma Using Mycobacteria

• Choi IS

• KMID: 2260678
• DOI: http://doi.org/10.4168/aair.2014.6.3.187

Abstract

No abstract available.

MeSH Terms

Asthma*

Reference

1. Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin response and atopic disorder. Science. 1997; 275:77–79.

2. von Mutius E, Pearce N, Beasley R, Cheng S, von Ehrenstein O, Björkstén B, Weiland S. International patterns of tuberculosis and the prevalence of symptoms of asthma, rhinitis, and eczema. Thorax. 2000; 55:449–453.

3. Grüber C, Meinlschmidt G, Bergmann R, Wahn U, Stark K. Is early BCG vaccination associated with less atopic disease? An epidemiological study in German preschool children with different ethnic backgrounds. Pediatr Allergy Immunol. 2002; 13:177–181.

4. García-Marcos L, Suárez-Varela MM, Canflanca IM, Garrido JB, Quirós AB, López-Silvarrey Varela A, Hernández GG, Guillén-Grima F, Díaz CG, González IH, Pena AA, Monge RB. BCG immunization at birth and atopic diseases in a homogeneous population of Spanish schoolchildren. Int Arch Allergy Immunol. 2005; 137:303–309.

5. Grüber C, Kulig M, Bergmann R, Guggenmoos-Holzmann I, Wahn U. MAS-90 Study Group. Delayed hypersensitivity to tuberculin, total immunoglobulin E, specific sensitization, and atopic manifestation in longitudinally followed early Bacille Calmette-Guérin-vaccinated and nonvaccinated children. Pediatrics. 2001; 107:E36.

6. Kim YJ, Kim HJ, Kang MJ, Yu HS, Seo JH, Kim HY, Park SJ, Lee YC, Hong SJ. Bacillus Calmette-Guérin suppresses asthmatic responses via CD4+CD25+ regulatory T cells and dendritic cells. Allergy Asthma Immunol Res. 2014; 6:201–207.

7. Herz U, Gerhold K, Grüber C, Braun A, Wahn U, Renz H, Paul K. BCG infection suppresses allergic sensitization and development of increased airway reactivity in an animal model. J Allergy Clin Immunol. 1998; 102:867–874.

8. Koh YI, Choi IS, Park SC, Kang KW. BCG infection during pre- sensitization or even post-sensitization inhibits airway sensitivity in an animal model of allergic asthma. J Korean Med Sci. 2000; 15:265–272.

9. Choi IS, Koh YI. Therapeutic effects of BCG vaccination in adult asthmatic patients: a randomized, controlled trial. Ann Allergy Asthma Immunol. 2002; 88:584–591.

10. Choi IS, Koh YI. Effects of BCG revaccination on asthma. Allergy. 2003; 58:1114–1116.

11. Choi IS, Han ER, Kim YJ, Yoon JY, Kim SS, Seo IK, Jang YJ, Park CS. Personal factors affecting therapeutic responses to BCG vaccination in asthmatics. Allergy Asthma Immunol Res. 2011; 3:178–185.

12. Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989; 299:1259–1260.

13. Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002; 347:911–920.

14. Umetsu DT, McIntire JJ, Akbari O, Macaubas C, DeKruyff RH. Asthma: an epidemic of dysregulated immunity. Nat Immunol. 2002; 3:715–720.

15. Zuany-Amorim C, Sawicka E, Manlius C, Le Moine A, Brunet LR, Kemeny DM, Bowen G, Rook G, Walker C. Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells. Nat Med. 2002; 8:625–629.

16. Li Q, Shen HH. Neonatal bacillus Calmette-Guérin vaccination inhibits de novo allergic inflammatory response in mice via alteration of CD4+CD25+ T-regulatory cells. Acta Pharmacol Sin. 2009; 30:125–133.

17. Orme IM, Andersen P, Boom WH. T cell response to Mycobacterium tuberculosis. J Infect Dis. 1993; 167:1481–1497.

18. Yoshida M, Leigh R, Matsumoto K, Wattie J, Ellis R, O'Byrne PM, Inman MD. Effect of interferon-γ on allergic airway responses in interferon-γ-deficient mice. Am J Respir Crit Care Med. 2002; 166:451–456.

19. Barlan I, Bahceciler NN, Akdis M, Akdis CA. Bacillus Calmette-Guérin, Mycobacterium bovis, as an immunomodulator in atopic diseases. Immunol Allergy Clin North Am. 2006; 26:365–377.

20. Han ER, Choi IS, Choi HG, Kim HJ. Therapeutic Effects of Mycobacterial Secretory Proteins Against Established Asthma in BALB/c Mice. Allergy Asthma Immunol Res. 2012; 4:214–221.

21. Kim YJ, Kim HJ, Jeong SK, Lee SH, Kang MJ, Yu HS, Jung YH, Seo JH, Kim BJ, Yu J, Park SJ, Lee YC, Hong SJ. A novel synthetic mycolic acid inhibits bronchial hyperresponsiveness and allergic inflammation in a mouse model of asthma. Allergy Asthma Immunol Res. 2014; 6:83–88.

22. Choi IS, Lin XH, Koh YA, Cui Y. BCG-induced dendritic cell responses and suppression of interleukin-5 production from T cells in atopic asthmatics. J Korean Med Sci. 2008; 23:628–634.

23. Shojaeian J1, Jeddi-Tehrani M, Dokouhaki P, Mahmoudi AR, Ghods R, Bozorgmehr M, Nikoo S, Bayat AA, Akhondi MM, Ostadkarampour M, Rezania S, Zarnani AH. Mutual helper effect in copulsing of dendritic cells with 2 antigens: a novel approach for improvement of dendritic-based vaccine efficacy against tumors and infectious diseases simultaneously. J Immunother. 2009; 32:325–332.