Korean J Med.  2010 Dec;79(6):705-709.

Concurrent renal and hepatic angiomyolipoma with pulmonary involvement in two patients with tuberous sclerosis

• Sung JY
• Na SY
• Jung JY
• Lee HH
• Chung WK
• Sung YM
• Chang JH

Abstract

Tuberous sclerosis (TS) involves multiple organs. Angiomyolipoma of the liver or kidney is one of the clinical manifestations of TS. However, coexistent renal and hepatic angiomyolipoma associated with TS is a rare condition. Pulmonary involvement is extremely rare, and occurs in only 0.1~1% of TS. We report two cases of concurrent renal and hepatic angiomyolipomas with pulmonary involvement in patients with TS. The first case was a 35 year-old woman who showed multiple angiomyolipomas in the liver and both kidneys and cystic parenchymal changes in the lungs. The other case was a 27-year-old woman who showed multiple angiomyolipomas in the liver and both kidneys, and multinodular pulmonary shadows. To the best of our knowledge, this is the first reported case of renal and hepatic angiomyolipomas associated with pulmonary involvement in Korea.

Keyword

Angiomyolipoma; Tuberous sclerosis; Lymphangioleiomyomatosis; Multifocal micronodular pneumocyte hyperplasia

MeSH Terms

Adult
Angiomyolipoma
Female
Humans
Kidney
Korea
Liver
Lung
Lymphangioleiomyomatosis
Tuberous Sclerosis