Korean J Med.
2010 Dec;79(6):686-690.
A case of hepatocellular carcinoma combined with solitary parathyroid metastasis
- Affiliations
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- 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School Medicine, Seoul, Korea. bik.kim@samsung.com
- 2Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School Medicine, Seoul, Korea.
Abstract
- Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide1). Extrahepatic metastasis of HCC is now increasing due to prolonged survival. Most extrahepatic HCC occurs in patients with advanced stages. The lung, abdominal lymph nodes, and bone are common sites of extrahepatic metastasis. However, the parathyroid gland has not been reported as a metastatic focus. We report the first case of parathyroid metastasis as the first single metastasis site of HCC and microscopic tumor-to-tumor metastasis to a parathyroid adenoma.