Korean J Med.  2011 Jun;80(Suppl 2):S305-S309.

Conservative Care was Successfully Used to Manage Acute Hepatitis A Infection with Blindness

Affiliations
  • 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.
  • 2Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.
  • 3Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea. cadevar@paran.com

Abstract

Hepatitis A is usually a mild, self-limiting illness, but in certain cases it can develop into a severe or fatal disease. The most common symptoms of acute hepatitis A virus (HAV) infection are fever, myalgia, nausea, vomiting, jaundice, and abdominal pain. Extrahepatic symptoms are rare, especially neurologic manifestations. We investigated a 34-year-old male who presented after suffering two days of fever, chills and general myalgia. His condition gradually deteriorated and he developed sudden blindness on day nine. This blindness lasted for 20 min and at this point abnormal brain images were observed. Initial tests for immunoglobulin M anti HAV were negative. These tests were repeated, later confirming acute HAV infection. After conservative management, the individual fully recovered. We report this extremely rare acute HAV infection case with metabolic encephalopathy exhibiting transient blindness.

Keyword

Hepatitis A; Encephalopathy; Blindness

MeSH Terms

Abdominal Pain
Adult
Blindness
Brain
Brain Diseases, Metabolic
Chills
Fever
Hepatitis
Hepatitis A
Hepatitis A Antibodies
Hepatitis A virus
Humans
Immunoglobulin M
Jaundice
Male
Nausea
Neurologic Manifestations
Stress, Psychological
Vomiting
Hepatitis A Antibodies
Immunoglobulin M
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