Korean J Nephrol.  2005 Nov;24(6):975-979.

A Case of C1q Mediated Glomerulonephritis Manifested by Asymptomatic Hematuria

• Ahn HS
• Ha TH
• Na HS
• Gil HW
• Yang JO
• Lee EY
• Hong SY

Abstract

C1q nephropathy is an immune complex glomerulonephritis defined by predominant mesangial C1q deposition and has no evidence of systemic lupus erythematosus. Patients are usually between the ages of 15 and 30 when diagnosed and have a nephrotic range proteinuria. C1q nephropathy in adult has not been reported yet in Korea. Also it may be accompanied by hematuria, but it is uncommonly manifested hematuria without proteinuria. We experienced a case of C1q mediated glomerulonephritis that manifested by asymptomatic hematuria in adult. A 47-years-old man visited our hospital complaining general weakness and fatigue. Microscopic hematuria was detected on routine examination of urinary sediment so that renal biopsy was carried out. Renal biopsy showed C1q mediated glomerulonephritis. We report a case of C1q mediated glomerulonephritis manifested by asymptomatic hematuria without proteinuria. C1q nephropathy should be added to the differential diagnosis of glomerulonephritis in patients with asymptomatic hematuria.

Keyword

C1q nephropathy; Hematuria

MeSH Terms

Adult
Antigen-Antibody Complex
Biopsy
Diagnosis, Differential
Fatigue
Glomerulonephritis*
Hematuria*
Humans
Korea
Lupus Erythematosus, Systemic
Proteinuria
Antigen-Antibody Complex