Korean J Nephrol.  2007 Nov;26(6):753-757.

A Cases of Paraganglioma in Bladder of Patient who Visited with Acute Renal Failure

Affiliations
  • 1Department of Internal Medicine, Seoul Medical Center, Korea. eoot35@hanmail.net
  • 2Department of Pathology, Seoul Medical Center, Korea.

Abstract

Pheochromocytoma is a catecholamines secreting tumor that usually appears in the adrenal medulla, sympathetic ganglia and extra-adrenal chromaffin tissue. About 10% of this disease is detected in the extra-adrenal chromaffin tissue which is called paraganglioma. The three major clinical symptoms of pheochromocytoma are headache, syncope and hypertension. Approximately 0.1% of hypertensive patients have pheochromocytoma. The extra-adrenal paraganglioma is found in abdominal sympathetic nerve ganglion or Zukerkandle's organ with great frequency, but it also appears, albeit rare, in the cervical ganglion, thoracic cavity, bladder, and pelvic cavity. Some cases of paraganglioma in bladder are being reported internationally, but domestic reports are rare. We report a case of paraganglioma originating in the urinary bladder of patient who visited with acute renal failure associated with malignant hypertension. We treated him with phenoxybenzamine and later with partial cystectomy. High blood pressure was well controlled and acute renal failure was resolved.

Keyword

Paraganglioma; Bladder; Malignant hypertension; Acute renal failure

MeSH Terms

Acute Kidney Injury*
Adrenal Medulla
Catecholamines
Cystectomy
Ganglia, Sympathetic
Ganglion Cysts
Headache
Humans
Hypertension
Hypertension, Malignant
Paraganglioma*
Paraganglioma, Extra-Adrenal
Phenoxybenzamine
Pheochromocytoma
Syncope
Thoracic Cavity
Urinary Bladder*
Catecholamines
Phenoxybenzamine
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