Korean J Med.
2003 Nov;65(Suppl 3):S689-S692.
A case of toxic hepatitis caused by the chinese diet food
- Affiliations
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- 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. hepatotoxicity@empal.com
- 2Department of Clinical Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.
- 3Department General Toxicology, NITR, KFDA, Seoul, Korea.
Abstract
- Recently over 500 victims with toxic hepatitis associated with some sort of Chinese diet food for weight reduction were developed in Japan, China, Singapore and Malaysia. These Chinese goods contain several kinds of Chinese herbs and fenfluramine, the well known anti-appetite drug. However, until today, it is not determined which component of the diet food is responsible for the hepatic injury. Nowadays, toxic hepatitis is frequently seen in daily practice, second only to viral origin in Korea. We present a 38-year-old woman who developed mixed cholestatic and hepatocellular injury after 5 week's ingestion of the Chinese diet food. The causality of this agent to the hepatotoxicity was assessed by RUCAM and M and V scale. Herein we described the clinical course and liver pathology of this patient.
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