Korean J Dermatol.  2001 Sep;39(9):1035-1037.

A Case of Acute Generalized Exanthematous Pustulosis

Affiliations
  • 1Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Acute generalized exanthematous pustulosis (AGEP) is initially termed by Beylot to describe a disease entity with sudden onset of amicrobial pustular eruption accompanied with fever and leukocytosis. A 58-year-old man presented with sudden onset of multiple, generally pinhead sized pustules on erythematous base scattered on trunk accompanied with fever. The patient had been on medication of cefotiam prior to skin eruption for 4 days after esophageal cancer operation. Histopathological study of a skin biopsy specimen revealed subcorneal pustules with a few neutrophils and few eosinophils in dermis. After discontinuation of cefotiam and systemic steroid medication for 5 days, the eruption resolved clearly without scars within 4 days.

Keyword

Acute generalized exanthematous pustulosis; Cefotiam

MeSH Terms

Acute Generalized Exanthematous Pustulosis*
Biopsy
Cefotiam
Cicatrix
Dermis
Eosinophils
Esophageal Neoplasms
Fever
Humans
Leukocytosis
Middle Aged
Neutrophils
Skin
Cefotiam
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