Korean J Dermatol.  2001 Sep;39(9):1014-1016.

A Case of Linear Hyperpigmentation after Bleomycin Treatment

Affiliations
  • 1Department of Dermatology, College of Medicine, Soonchunhyang University Seoul, Korea. happyskin@yahoo.co.kr

Abstract

Bleomycin, an antitumor antibiotic, has several dose-related skin toxicities, including hyperpigmentation, sclerosis, gangrenes, nail changes, and erythema in certain selected skin sites. A case of hyperpigmentation in a linear pattern due to in tavenous injection of bleomycin in a 37-year-old man with squamous cell carcinoma at nasopharynx is described. After 9 months since bleomycin chemotherapy started, dark brownish colored linear hyperpigmentation developed along veins of the skin of both arms.

Keyword

Bleomycin; Linear hyperpigmentation

MeSH Terms

Adult
Arm
Bleomycin*
Carcinoma, Squamous Cell
Drug Therapy
Erythema
Gangrene
Humans
Hyperpigmentation*
Nasopharynx
Sclerosis
Skin
Veins
Bleomycin
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