Korean J Dermatol.  2002 Mar;40(3):308-310.

A Case of Atypical Benign Fibrous Histiocytoma

Affiliations
  • 1Department of Dermatology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. hjpark@cmc.cuk.ac.kr

Abstract

Benign fibrous histiocytomas are relatively common nodules that are histologically characterized by a proliferation of fibroblastic and histiocytic cells in the dermis. Rarely, some show such cellular atypia that there are some difficulties in differentiating the lesion from sarcoma. Herein we report a 42-year-old man with asymptomatic, solitary, 11 cm sized, red-to-brown colored, broad-based, and firm nodule on the right forearm for about 2 years. Histologically, the lesion was composed of histiocytes, fibroblasts and pleomorphic, bizarre multinucleated giant cells. Despite the cellular atypia, mitotic figures were not found.

Keyword

Atypical benign fibrous histiocytoma; Pleomorphism

MeSH Terms

Adult
Dermis
Fibroblasts
Forearm
Giant Cells
Histiocytes
Histiocytoma, Benign Fibrous*
Humans
Sarcoma
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