Korean J Dermatol.
2003 Jan;41(1):104-107.
A Case of Nasal Glioma
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. derma@vincent.cuk.ac.kr
- 2Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- Nasal glioma is a rare, benign, congenital tumor, which is ectopic sequested brain tissue that has lost its intracranial connection. It is thought to be the result of an abnormality in embryonic development. A 2-month-old female patient presented with firm, noncompressible, pinkish, 0.6 cm-diameter, protruding mass on the glabella from birth. No intracranial connection was found by MRI. Histopathological finding showed an unencapsulated pale-staining fibrillary glial tissue, which contains astrocytes and some neurons. Immunohistochemically, the glial tissue and astrocytes were positive for GFAP(glial fibrillary acidic protein), and neurons were positive for NSE(neuron-specific enolase).