Korean J Dermatol.  2003 Jan;41(1):104-107.

A Case of Nasal Glioma

Affiliations
  • 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. derma@vincent.cuk.ac.kr
  • 2Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Nasal glioma is a rare, benign, congenital tumor, which is ectopic sequested brain tissue that has lost its intracranial connection. It is thought to be the result of an abnormality in embryonic development. A 2-month-old female patient presented with firm, noncompressible, pinkish, 0.6 cm-diameter, protruding mass on the glabella from birth. No intracranial connection was found by MRI. Histopathological finding showed an unencapsulated pale-staining fibrillary glial tissue, which contains astrocytes and some neurons. Immunohistochemically, the glial tissue and astrocytes were positive for GFAP(glial fibrillary acidic protein), and neurons were positive for NSE(neuron-specific enolase).

Keyword

Nasal glioma

MeSH Terms

Astrocytes
Brain
Embryonic Development
Female
Glioma*
Humans
Infant
Magnetic Resonance Imaging
Neurons
Parturition
Pregnancy
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