Korean J Dermatol.  2005 May;43(5):655-659.

Two Cases of Dapsone Syndrome

Affiliations
  • 1Department of Dermatology, Cheju National University, College of Medicine, Jeju, Korea. rulidroxim@hanmail.net
  • 2Department of Rheumatology, Cheju National University, College of Medicine, Jeju, Korea.

Abstract

Dapsone syndrome is a rare, potentially fatal hypersensitivity reaction to dapsone, presenting with a triad of fever, a rash, and internal organ involvement. We describe 2 cases of dapsone syndrome presenting like viral exanthem. Two male patients presented with a spiking fever and generalized eruptions, 2 to 3 weeks after initiation of dapsone. Clinicians should be aware of dapsone syndrome in patients who are on dapsone therapy and who have abnormal liver tests, fever and a rash.

Keyword

Dapsone syndrome

MeSH Terms

Dapsone*
Exanthema
Fever
Humans
Hypersensitivity
Liver
Male
Dapsone
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