Korean J Infect Dis.  1999 Jun;31(3):247-251.

A Case of Mediastinal Tuberculous Abscess and Lymphadenitis after Bone Marrow Transplantation

• Kim CW
• Lim DJ
• Jang T
• Sohn TS
• Lee DG
• Kim MY
• Choi JH
• Shin WS
• Kim CC

Abstract

After bone marrow transplantation (BMT), recipients can be complicated by infectious or non-infectious chest lesions such as mycobacterial infections or post- transplant lymphoproliferative disorders (PTLDs). BMT recipients usually face a lot of risks of mycobacterial infection because they have severely impaired cell- mediated immunity as a result of their underlying disease, chemotherapy, radiotherapy, acute or chronic graft-versus-host diesase (GVHD) and their treatment. We report a case of mediastinal tuberculous abscess and lymphadenitis after BMT, which mimicks PTLDs. 20 months before admission, BMT was performed on a 41 year-old woman who was diagnosed as chronic myelocytic leukemia. She showed acute and chronic GVHD with several infections of bacteria or viruses after BMT. In endemic area of tuberculosis such as Korea, PTLDs should be differentiated from pulmonary tuberculosis and tuberculous lymphadenitis.

Keyword

Bone marrow transplantation; Mycobacterial infection; Mediastinal abscess; Post-transplant lymphoproliferative disorders

MeSH Terms

Abscess*
Adult
Bacteria
Bone Marrow Transplantation*
Bone Marrow*
Drug Therapy
Female
Humans
Korea
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Lymphadenitis*
Lymphoproliferative Disorders
Radiotherapy
Thorax
Tuberculosis
Tuberculosis, Lymph Node
Tuberculosis, Pulmonary