Korean J Dermatol.  2009 May;47(5):570-575.

Neuro-Sweet's Syndrome with Central Nervous System Involvement

• Kim JW

Abstract

Sweet's syndrome is an acute reactive condition that is characterized by fever, neutrophilic leukocytosis, erythematous tender edematous plaques or papules, and a dense dermal infiltrate of mature neutrophils. Although the extracutaneous manifestations of Sweet's syndrome are commonly seen in the joints and eyes, the central nervous system is rarely involved. A novel concept designated "Neuro-Sweet's syndrome" has recently been proposed for those cases of Sweet's syndrome that involve the central nervous system. It is essential to evaluate the skin eruptions in patients with recurrent meningoencephalitis of an unknown origin in order to avoid unnecessary empiric therapy. Herein, we report on two men who suffered from acute recurrent meningoencephalitis and they were subsequently diagnosed as having Neuro-Sweet's syndrome.

Keyword

entral nervous system; Neuro-Sweet's syndrome

MeSH Terms

Central Nervous System
Eye
Fever
Humans
Joints
Leukocytosis
Male
Meningoencephalitis
Neutrophils
Skin
Sweet Syndrome