Korean J Dermatol.  2009 Jun;47(6):706-709.

A Case of Kikuchi's Histiocytic Necrotizing Lymphadenitis Associated with Systemic Lupus Erythemasus

Affiliations
  • 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. jpark@catholic.ac.kr

Abstract

Kikuchi's disease (KD), histiocytic necrotizing lymphadenitis, isa benign and self-limited disease which mainly affects young women. KD has been rarely described in association with systemic lupus erythematosus (SLE), and its diagnosis can precede, postdate or coincide with the diagnosis of SLE. The tendency of flare-up of lupus activity with the onset of KD and the simultaneous occurrence of these two diseases suggest that they are not independent events. Herein, we report a case of KD associated with SLE in an 18-year-old female who showed tender erythematous papules on both upper extremities accompanied by cervical lymphadenopathy. The histopathologic examination of lymph nodes showed histiocytic necrotizing lymphadenitis.

Keyword

Kikuchi's disease; Systemic lupus erythematosus

MeSH Terms

Adolescent
Female
Histiocytic Necrotizing Lymphadenitis
Humans
Lupus Erythematosus, Systemic
Lymph Nodes
Lymphatic Diseases
Upper Extremity
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