Korean J Dermatol.  2012 Sep;50(9):814-817.

Multiple Trichoepithelioma Improved by Intralesional Bleomycin Injection

• Son HH
• Jung SW
• Sim HS
• Lee SK

Abstract

Multiple trichoepithelioma is a benign adnexal neoplasm characterized by the presence of many small papules that appear predominantly on the face. Clinical improvement have been demonstrated after several treatments such as carbon dioxide laser, cryotherapy, dermabrasion, and argon laser. However, these destructive methods have various disadvantages. We report a case of multiple trichoepithelioma treated with an intralesional bleomycin injection. Fewer lesions without scars and cosmetic improvements were observed. Bleomycin is a cytotoxic antitumor antibiotic that can be injected intralesionally by transcutaneous administration and displays excellent results for treating malignancies including skin tumors. We believe that intralesional bleomycin injection is an effective treatment option for this condition, and an easy method to conduct at the outpatient clinic.

Keyword

Bleomycin; Multiple trichoepithelioma

MeSH Terms

Administration, Cutaneous
Ambulatory Care Facilities
Argon
Bleomycin
Cicatrix
Cosmetics
Cryotherapy
Dermabrasion
Lasers, Gas
Skin
Argon
Bleomycin
Cosmetics