Korean J Health Promot.
2012 Jun;12(2):75-82.
Factors Associated with Compliance Using Diamicron in Patients with Type 2 Diabetes
- Affiliations
-
- 1Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. youngkim@amc.seoul.kr
- 2Department of Family Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
- 3Deparment of Family Medicine, Dongsan Medical Center, Kemyung University School of Medicine, Daegu, Korea.
- 4Department of Family Medicine, St. Vincent's Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea.
- 5Department of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea.
Abstract
- BACKGROUND
Diabetes mellitus (DM) is one of the most important chronic diseases in public health, thus optimal management of this condition is crucial. For this purpose, oral hypoglycemic agents (OHA) are commonly prescribed with their consistent use being mandatory to maintain adequate blood glucose levels. We aimed to evaluate the compliance with OHA in patients with DM, and to determine the factors associated with compliance.
METHODS
From March 2006 to December 2007, we enrolled patients with type 2 DM who were newly diagnosed or had discontinued OHAs for more than four weeks. For OHA, diamicron was prescribed to the participants and response to medication was evaluated by physicians after 12 weeks. Compliance was defined as patients taking diamicron continuously or stopping the medication due to well-controlled blood sugar levels. Demographic characteristics, anthropometric measurements, fasting glucose, and lipid profiles were collected and analyzed.
RESULTS
The mean age of our 326 subjects was 56.0+/-9.9 years and 74.5% was defined to be compliant. Logistic regression analysis adjusting for age and sex revealed that combined medication use (odd ratio [OR], 2.03; 95% confidence interval [CI], 1.04-3.97) and diabetes-related nutritional education (OR, 2.08; 95% CI, 1.08-4.03) (P<0.05) were factors associated with compliance with OHA.
CONCLUSIONS
About three quarters of the DM patients in our study, using diamicron for the first time, showed compliance after 12 weeks of treatment. Concomitant medications and diabetes-related nutrition education were associated with compliance.
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