Korean J Dermatol.  2015 Jan;53(1):45-48.

Sister Mary Joseph Nodule as a Metastasis of Gallbladder Carcinoma

• Ha JM
• Yoon JH
• Cho EB
• Park GH
• Park EJ
• Kwon IH
• Kim KH
• Kim KJ

Abstract

Cutaneous metastasis into the umbilicus, known as a Sister Mary Joseph nodule, is quite rare. Gastric adenocarcinoma is the most common primary origin overall, whereas gynecologic tumors such as ovarian cancer are the leading cause in women. In most cases, the nodule manifests after the primary tumor had been diagnosed. In rare cases, however, it serves as the first sign of the underlying malignancy. Here, we report the case of a 59-year-old woman who presented with a nodule on the umbilicus and was diagnosed with metastatic adenocarcinoma originating in the gallbladder.

Keyword

Gallbladder cancer; Metastasis; Sister Mary Joseph nodule

MeSH Terms

Adenocarcinoma
Female
Gallbladder Neoplasms
Gallbladder*
Humans
Middle Aged
Neoplasm Metastasis*
Ovarian Neoplasms
Siblings*
Umbilicus