Korean J Dermatol.  2015 Sep;53(8):638-642.

Lymphomatoid Papulosis Following Anaplastic Large Cell Lymphoma in a Child

Affiliations
  • 1Department of Dermatology, Yeungnam University College of Medicine, Daegu, Korea. dhshin@med.yu.ac.kr
  • 2Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea.

Abstract

Patients with lymphomatoid papulosis have an increased risk (approx. 5% to 20%) of developing a malignant lymphoma such as mycosis fungoides, anaplastic large cell lymphoma (ALCL) and Hodgkin's disease before, during, or after lymphomatoid papulosis occurs. However, it is very rare that lymphomatoid papulosis occurs after ALCL, especially in childhood. An 11-year-old boy who had been diagnosed with ALCL 3 years prior and treated with chemotherapy and peripheral blood stem cell transplantation developed multiple scaly papules on his trunk and both extremities. Histopathologic and immunohistochemical examination of the scaly papules revealed lymphomatoid papulosis. The patient was cured with narrow band UVB treatment and there has been no relapse in lesions 10 years later. We report a case of lymphomatoid papulosis following allogenic stem cell transplantation for ALCL.

Keyword

Anaplastic large cell lymphoma; Lymphomatoid papulosis

MeSH Terms

Child*
Drug Therapy
Extremities
Hodgkin Disease
Humans
Lymphoma
Lymphoma, Large-Cell, Anaplastic*
Lymphomatoid Papulosis*
Male
Mycosis Fungoides
Peripheral Blood Stem Cell Transplantation
Recurrence
Stem Cell Transplantation
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