J Gynecol Oncol.  2009 Jun;20(2):126-128. 10.3802/jgo.2009.20.2.126.

A case of mucinous adenocarcinoma arising from retroperitoneal teratoma treated with chemoradiation

• Kim JH
• Lee TS
• Oh HK
• Choi YS

• KMID: 2245097
• DOI: http://doi.org/10.3802/jgo.2009.20.2.126

Abstract

Retroperitoneal teratoma with malignant transformation is a rare condition in adults. Its most common malignant transformation is into a squamous cell carcinoma, but rarely into a mucinous adenocarcinoma. Postoperative treatment of mucinous adenocarcinoma arising from teratomas has not been established due to its rare incidence. Here we present a case of retroperitoneal mucinous adenocarcinoma arising from a teratoma in the presacral area. Operative and postoperative managements are described with a brief review of the literatures.

Keyword

Retroperitoneal neoplasms; Teratoma; Mucinous cystadenocarcinoma; Chemoradiotherapy

MeSH Terms

Adenocarcinoma, Mucinous
Adult
Carcinoma, Squamous Cell
Chemoradiotherapy
Cystadenocarcinoma, Mucinous
Humans
Incidence
Mucins
Retroperitoneal Neoplasms
Teratoma
Mucins

Figure

• 

  Fig. 1 MRI. Retroperitoneal cystic mass with multiple septations (T). Large bowel (arrow) is displaced upward by mass. This finding suggests its retroperitoneal location.

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  Fig. 2 Gross histopathologic findings show multilocular cystic mass that is partially lined by whitish gray mucosa and has focal hemorrhage.

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  Fig. 3 Microscopic findings. (A) Well to poorly differentiated adenocarcinoma mixed with mucinous carcinoma (H&E stain, ×100), (B) ciliated pseudostratified columnar epithelium (H&E stain, ×100), (C) stratified squamous epithelium (H&E stain, ×100).

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  Fig. 4 MRI shows ill-defined solid tumor (arrow) with high signal intensity just beneath abdominal skin incision site (arrow head).

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