A Case of Verrucous Carcinoma of Vulva

Park, J E; Kang, J B; Sim, J W; Kim, H B; Lee, K Y; Kang, S W

Abstract

Verrucous Carcinoma(VC) of the female genital tract is a rare lesion, primarily affecting postmenopausal women. A case of VC of the vulva is reported. VC is a variant of squamous cell carcinoma that has distinctive clinical and pathologic characteristic, slowly growing locally invasive, non-metastasis pushing tumor with a rather benign histologic appearence, VC of the vulvar have often invaded deeply into adjacent tissues, demanding extensive surgery, and commonly associated with local recurrence. There still exist diagnostic difficulties and treatment is a matter of debate. It seems logical to treat the tumor by wide local excision. Radiation therapy should be contraindicated, and local application of podophyllin, bleomycin and cryosurgery are ineffective. Authors present a case of verrucous carcinoma of vulva, and literature is reviewed. The clinical and histologic features are described and therapeutic aspects are discussed on the basis of the literature.