Korean J Gastrointest Endosc.  2000 Oct;21(4):780-785.

Cholangioscopic Findings of Various Bile Duct Tumors According to Histology

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
  • 2Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Abstract

BACKGROUND/AIMS
The technique of cholangioscopy has been used in the treatment of bile duct stones or for the diagnosis of various bile duct tumors. However, the cholangioscopic characteristics of the various types of bile duct tumors have not yet been clearly described. Therefore, we analyzed the results of our cholangioscopic examinations and classified the cholangioscopic findings according to tumor histology.
METHODS
The cholangioscopic finding from 111 patients who had benign or malignant bile duct tumors were reviewed. The mucosal changes, the presence of neovascularization, and the patterns of luminal narrowing were analyzed and compared with the histologic diagnosis.
RESULTS
Bile duct adenocarcinoma can be classified into three different types according to the cholangioscopic findings: nodular, papillary, and infiltrative. Bile duct adenoma, hepatocellular carcinoma and other types of bile duct cancer such as mucin-hypersecreting cholangiocarcinoma, biliary cystadenocarcinoma, squamous cell carcinoma also presented with their unique cholangioscopic characteristics.
CONCLUSIONS
Bile duct tumors seem to show characteristic cholangioscopic findings according to their histology. Cholangioscopic examination seems to be a useful technique in the differential diagnosis of bile duct tumors.

Keyword

Cholangioscopy; Bile duct tumor

MeSH Terms

Adenocarcinoma
Adenoma, Bile Duct
Bile Duct Neoplasms
Bile Ducts*
Bile*
Carcinoma, Hepatocellular
Carcinoma, Squamous Cell
Cholangiocarcinoma
Cystadenocarcinoma
Diagnosis
Diagnosis, Differential
Humans
Phenobarbital
Phenobarbital
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