Korean J Anesthesiol.  1985 Mar;18(1):92-97.

Effects of Preoxygenation during induction of General Anesthesia

• Chae YU
• Park JW

Abstract

After the description of the necessity of denitrogenation in rebreathing anesthesia circuits some decades ago, many methods were recommended for techniques of ventilation with oxygen before induction of anesthesia for the purpose of maintaining arterial oxygenation during laryngoscopy and tracheal intubation . In this point of view, we compared PaO2, MAP, PaCO2, pH of non-preoxgenation group(oxygen was given after succinylcholine was injected) with those of preoxygenation group(owygen was given after thiopental sodium was injected). The cases were selected randomly who blongs to ASA class l or ll(without cardiopulmonary abnormalities) and ages betweens 27 years and 66 years old. Before induction of general anesthesia, we cannulated radial artery after Allen's test and sampled arterial blood before anesthesia, after thiopenthal and succinylcholine were injected respectively, when tracheal intubation was done in the two groups and measured PaO2, PaCO2, MAP, pH respectively. PaCO2, MAP, pH changes in the two groups were not significant and of no clinical significanses. PaO2 after tracheal intubation showed marked increase in preoxygenation group compared to non-preoxygenation group but mean PaO2 was maintained within normal range in non-preoxygenation group with the apnetic period of tracheal intubation. WE found that non-preoxygenated patients also had normal range of PaO2 during the whole process of induction of anesthesis. But I think preoxygenation technique of any method can reserve more time and will do more effectively, especially when times consuming events of difficult intubation of any reason occurs.

MeSH Terms

Aged
Anesthesia
Anesthesia, Closed-Circuit
Anesthesia, General*
Humans
Hydrogen-Ion Concentration
Intubation
Laryngoscopy
Oxygen
Radial Artery
Reference Values
Succinylcholine
Thiopental
Ventilation
Oxygen
Succinylcholine
Thiopental