Korean J Gastroenterol.
2000 Apr;35(4):405-412.
Clinical Value of Marshmallow Esophagography in Detecting
Esophageal Dysmotility
Abstract
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BACKGROUND/AIMS: We reported previously that marshmallow esophagography
was more sensitive than conventional esophagography in evaluation of esophageal
symptoms. To verify our previous study, we have investigated the clinical value
of marshmallow esophagography in detecting esophageal dysmotility. MERHODS:
Seventy-eight symptomatic patients who showed no organic disorders on esophagoscopy
or conventional esophagography underwent esophageal manometry and marshmallow
esophagography within one week. Forty-one of the patients also underwent esophageal
transit scintigraphy. Marshmallow transit was considered normal when it passed
the esophagus within 30 seconds on the supine position. Abnormal marshmallow
transit was graded as mild, moderate, and severe. RESULTS: The results of
esophageal manometry were normal in 30 of 52 (57.7%) subjects with normal
marshmallow transit, whereas the results were abnormal in 19 of 26 (73.1%)
patients with abnormal marshmallow transit (x2=5.405, p=0.02). The grade
of marshmallow transit was correlated to the degree of esophageal dysmotility
manometrically (x2M-H=7.588, p<0.01). The percentage of abnormal marshmallow
transit was significantly higher in patients with achalasia, diffuse esophageal
spasm, or non-specific esophageal motility disorder than in normal subjects.
The grade of marshmallow transit was correlated with the scintigraphic residual
fractions. CONCLUSIONS: These findings support that marshmallow esophagography
would be useful as one of good functional methods for detecting esophageal dysmotility.