Korean J Anesthesiol.  1987 Aug;20(4):492-499. 10.4097/kjae.1987.20.4.492.

The Effect of Intravenons Lidoeaine on the Increase in Intraoeular Fresaure Inluced by Traeheal Intubation

Affiliations
  • 1Department of Anesthesiology, Chonbuk National University College of Medicine, Chonju, Korea.

Abstract

To investigate the effect of lidocaine on the intraocular pleasure during induction of general anestheaia, intraocular pressure (lOP) was measured together with mean arterial pressure (MAP) , pulse rate, before and after intratraoheal intubation under several condit-ions (saline 5cc, lidocaine, 2 mg/kfr, lidocaine 2 mg/kg plus succinlrcholine 1 mg/kg). The results were as follows 1) Changes in mean arterial Preesure was not significantly different between lidocaine-treated group and non-treated group (p <0.05), 2) Changes in pluse rate was also not significantly different between lidocaine-treated group and non-treated group (p<0.05). 3) A decrease in lOP was net statistically significant after either lidocaine or saline administration comparing with the control baseline level. 4) lOP was markedly increased above the control baseline level after succinylcholine (S.C.C.) administration.5) A increase in lOP produced by intratracheal intubation wart reduced significantly by pretreatment with lidocaine comparing with non-treated group (P<0.01). 6) Simultaneous administration of lidocaine and succinylcholine did not prevent increase in lOP produced by intratracheal incubation. The abode data suggest that it would be most preferable to intuhate the patients under the general anesthesia with lidocaine pretreatment without using succinlycholine in the patients with eye hall Perforation or the patients who have recent surgical ocular incision.


MeSH Terms

Anesthesia, General
Arterial Pressure
Heart Rate
Humans
Intraocular Pressure
Intubation*
Intubation, Intratracheal
Lidocaine
Pleasure
Succinylcholine
Warts
Lidocaine
Succinylcholine
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