Korean J Anesthesiol.
1993 Apr;26(2):310-313. 10.4097/kjae.1993.26.2.310.
Blood Concentration of Lidocaine after Subarachnoid Administration
- Affiliations
-
- 1Department of Anesthesiology, Keimyung University School of Medicine, Taegu, Korea.
- KMID: 2239260
- DOI: http://doi.org/10.4097/kjae.1993.26.2.310
Abstract
- Ten healthy adult female patients scheduled for elective abdominal hysterectomy were evaluated for their rates and degrees of absorption following subarachnoid administration of 150 mg of 5% lidocaine in 5% dextrose solution. The mean blood concentrations of lidocaine measured at 5, 15, 30, 60 and 90 minutes after subarachnoid administration were 0.34+/-0.23, 0.78+/-0.27, 1.10+/-0.26, 1.24+/-0.24 and 1.07+/-0.19 mcg/ ml, respectively. The mean values of Cmax and Tmax obtained from these measurements were 1.30+/- 0.21 mcg/ml and 57+/-17 minutes, respectively. These results revealed that in comparison with other regional administration, absorption of lidocaine follwing subarachnoid injection is slower.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The Effect of Bupivacaine on the Methemoglobin Formation
- Plasma Concentrations of Lidocaine Associated with Caudal Anesthesia
- Effects of Epinephrine on Blood Concentration of Lidocaine and Epidural Block during Cesarean Section
- Spinal Anesthesia Using Lidocaine / Meperidine Mixture for Cesarean Section
- Effects of Added Epinephrine on Plasma Concentration of Lidocaine Following Epidural Anesthesia
