Korean J Anesthesiol.
2007 Jul;53(1):48-53. 10.4097/kjae.2007.53.1.48.
Optimal Dose of Remifentanil to Attenuate Cardiovascular Responses to Laryngoscopic Double-lumen Endobronchial Intubation
- Affiliations
-
- 1Department of Anesthesiology and Pain Medicine, School of Medicine, Keimyung University, Daegu, Korea. kimjin00@dsmc.or.kr
- KMID: 2238297
- DOI: http://doi.org/10.4097/kjae.2007.53.1.48
Abstract
-
BACKGROUND: The purpose of the present study was to determine the optimal dose of bolus remifentanil to attenuate hemodynamic changes to laryngoscopic double-lumen endobronchial intubation.
METHODS
A total of 80 ASA I or II patients requiring double-lumen endobronchial intubation were randomly assigned to receive normal saline (NS) or one of the three different doses (0.5microgram/kg (group R0.5), 1.0microgram/kg (group R1.0) or 2.0microgram/kg (group R2.0)) of remifentanil. Study drugs for each group were administered over 30 seconds after induction of anesthesia with thiopental sodium and rocuronium. Laryngoscopic endobronchial intubation was carried out 90 seconds after the administration of study drug. Arterial blood pressure and heart rate were recorded at preanesthetic baseline, preintubation, postintubation, and every one minute during the initial 5 minute period after intubation.
RESULTS
Mean arterial pressure at postintubation period increased significantly compared to baseline value in group NS, R0.5, and R1.0, but there were no significant changes in group R2.0. Heart rate showed significant increase in comparison to baseline value at every postintubation period in group NS, R0.5, R1.0, with no significant changes in group R2.0.
CONCLUSIONS
We suggest that 2.0microgram/kg of remifentanil attenuate the hemodynamic changes to double-lumen endobronchial intubation without adverse effect.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The effect-site concentration of remifentanil for blunting hemodynamic responses: comparative study in single-lumen endotracheal and double-lumen endobronchial intubation
- Optimal Dose of Remifentanil to Suppress Cardiovascular Responses to Laryngoscopic Endotracheal Intubation
- Effect-site concentration of remifentanil for blunting hemodynamic response to double lumen endobronchial intubation during target controlled infusion-total intravenous anesthesia using propofol with remifentanil
- Effects of Remifentanil and Alfentanil on Cardiovascular Responses to Laryngoscopy and Double-lumen Endobronchial Intubation
- Unexpected folding of the endobronchial segment of double-lumen tube during intubation: A case report
