Korean J Anesthesiol.  2003 Jul;45(1):47-53. 10.4097/kjae.2003.45.1.47.

Hemodynamic and Metabolic Changes Induced by Tourniquet Release during Both Total Knee Replacement Arthroplasty

• Park SJ
• Kim SY

• KMID: 2236738
• DOI: http://doi.org/10.4097/kjae.2003.45.1.47

Abstract

BACKGROUND: A tourniquet is usually used for total knee replacement arthroplasty (TKR) to provide a bloodless surgical field. However, hemodynamic and metabolic changes result from the ischemia after application of a tourniquet. Moreover, the hemodynamic and metabolic effects of tourniquet application during both TKR under general anesthesia have been rarely reported.
METHODS
Fifteen patients undergoing both TKR were studied during general anesthesia. Hemodynamic and metabolic parameters were measured before inflating the tourniquet, just before release of the tourniquet and 3, 6, 15 min after tourniquet release. Stroke volume (SV), cardiac index (CI), systemic vascular resistance (SVR) and end-tidal CO2 (ETCO2) were measured using a non-invasive cardiac output monitor.
RESULTS
Mean arterial pressure (MAP) decreased after tourniquet release, but was not different from MAP before tourniquet inflation. After tourniquet release, central venous pressure, SVR, arterial pH, bicarbonate and calcium decreased significantly (P <0.05), and heart rate, CI, ETCO2, PaCO2 and potassium increased significantly (P <0.05). But, the hemodynamic and metabolic changes after tourniquet release in the subsequent TKR were not affected by those after tourniquet release in the antecedent TKR.
CONCLUSIONS
During both TKR, although there was no difference in the hemodynamic and metabolic changes after tourniquet release between the antecedent and the subsequent TKR, there were significant hemodynamic and metabolic changes after tourniquet release. These findings indicate the need for more active hemodynamic and metabolic monitoring in patients with a compromised cardiopulmonary function.

Keyword

both total knee replacement arthroplasty; hemodynamic; metabolic; non-invasive cardiac output monitor; release of tourniquet

MeSH Terms

Anesthesia, General
Arterial Pressure
Arthroplasty*
Arthroplasty, Replacement, Knee*
Calcium
Cardiac Output
Central Venous Pressure
Heart Rate
Hemodynamics*
Humans
Hydrogen-Ion Concentration
Inflation, Economic
Ischemia
Potassium
Stroke Volume
Tourniquets*
Vascular Resistance
Calcium
Potassium