Korean J Fam Med.  2015 Nov;36(6):335-340. 10.4082/kjfm.2015.36.6.335.

The Correlation between the Triglyceride to High Density Lipoprotein Cholesterol Ratio and Computed Tomography-Measured Visceral Fat and Cardiovascular Disease Risk Factors in Local Adult Male Subjects

• Park HR
• Shin SR
• Han AL
• Jeong YJ

• KMID: 2235226
• DOI: http://doi.org/10.4082/kjfm.2015.36.6.335

Abstract

BACKGROUND
We studied the association between the triglyceride to high-density lipoprotein cholesterol ratio and computed tomography-measured visceral fat as well as cardiovascular risk factors among Korean male adults.
METHODS
We measured triglycerides, high density lipoprotein cholesterol, body mass, waist circumference, fasting plasma glucose, hemoglobin A1c, systolic blood pressure, diastolic blood pressure, visceral fat, and subcutaneous fat among 372 Korean men. The visceral fat and subcutaneous fat areas were measured by computed tomography using a single computed tomography slice at the L4-5 lumbar level. We analyzed the association between the triglyceride to high density lipoprotein cholesterol ratio and visceral fat as well as cardiovascular risk factors.
RESULTS
A positive correlation was found between the triglyceride to high density lipoprotein cholesterol ratio and variables such as body mass index, waist circumference, fasting plasma glucose, hemoglobin A1c, visceral fat, and the visceral-subcutaneous fat ratio. However, there was no significant correlation between the triglyceride to high density lipoprotein cholesterol ratio and subcutaneous fat or blood pressure. Multiple logistic regression analyses revealed significant associations between a triglyceride to high density lipoprotein cholesterol ratio > or =3 and diabetes, a body mass index > or =25 kg/m2, a waist circumference > or =90 cm, and a visceral fat area > or =100 cm2. The triglyceride to high density lipoprotein cholesterol ratio was not significantly associated with hypertension.
CONCLUSION
There were significant associations between the triglyceride to high density lipoprotein cholesterol ratio and body mass, waist circumference, diabetes, and visceral fat among a clinical sample of Korean men. In the clinical setting, the triglyceride to high density lipoprotein cholesterol ratio may be a simple and useful indicator for visceral obesity and cardiovascular disease.

Keyword

Triglyceride; Cholesterol, HDL; Intra-Abdominal Fat; Computed Tomography

MeSH Terms

Adult*
Blood Glucose
Blood Pressure
Body Mass Index
Cardiovascular Diseases*
Cholesterol
Cholesterol, HDL*
Fasting
Humans
Hypertension
Intra-Abdominal Fat*
Lipoproteins
Logistic Models
Male*
Obesity, Abdominal
Risk Factors*
Subcutaneous Fat
Triglycerides*
Waist Circumference
Cholesterol
Cholesterol, HDL
Lipoproteins
Triglycerides