Korean J Gastroenterol.  2014 Jun;63(6):386-388. 10.4166/kjg.2014.63.6.386.

Can Acid Pocket-targeting Alginate-antacid (Gaviscon Double Action) Relieve Upper Gastrointestinal Symptoms in Gastro-oesophageal Reflux Disease?

Affiliations
  • 1Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. mipark@kosinmed.or.kr

Abstract

No abstract available.


MeSH Terms

Alginates/*therapeutic use
Aluminum Hydroxide/*therapeutic use
Antacids/*therapeutic use
Female
Gastroesophageal Reflux/*drug therapy
Humans
Male
Silicic Acid/*therapeutic use
Sodium Bicarbonate/*therapeutic use
Alginates
Aluminum Hydroxide
Antacids
Silicic Acid
Sodium Bicarbonate

Reference

References

1. Kahrilas PJ, McColl K, Fox M, et al. The acid pocket: a target for treatment in reflux disease? Am J Gastroenterol. 2013; 108:1058–1064.
Article
2. Mandel KG, Daggy BP, Brodie DA, Jacoby HI. Review article: algi-nate-raft formulations in the treatment of heartburn and acid reflux. Aliment Pharmacol Ther. 2000; 14:669–690.
Article
3. Thomas E, Wade A, Crawford G, Jenner B, Levinson N, Wilkinson J. Randomised clinical trial: relief of upper gastrointestinal symptoms by an acid pocket-targeting alginate-antacid (Gaviscon Double Action) – a double-blind, placebo-controlled, pilot study in gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2014; 39:595–602.
Article
4. Jung HK, Hong SJ, Jo YJ, et al. Korean Society of Neurogastroenterology and Motility. Updated guidelines 2012 for gastroesophageal reflux disease. Korean J Gastroenterol. 2012; 60:195–218.
Article
5. Choung RS, Locke GR 3rd, Schleck CD, Zinsmeister AR, Talley NJ. Overlap of dyspepsia and gastroesophageal reflux in the general population: one disease or distinct entities? Neurogastroenterol Motil. 2012; 24:229–234. e106.
Article
6. Eslick GD, Talley NJ. Gastroesophageal reflux disease (GERD): risk factors, and impact on quality of life-a population-based study. J Clin Gastroenterol. 2009; 43:111–117.
7. Fletcher J, Wirz A, Young J, Vallance R, McColl KE. Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal. Gastroenterology. 2001; 121:775–783.
Article
8. Clarke AT, Wirz AA, Seenan JP, Manning JJ, Gillen D, McColl KE. Paradox of gastric cardia: it becomes more acidic following meals while the rest of stomach becomes less acidic. Gut. 2009; 58:904–909.
Article
9. Kahrilas PJ, Lin S, Chen J, Manka M. The effect of hiatus hernia on gastro-oesophageal junction pressure. Gut. 1999; 44:476–482.
Article
10. Han SH, Hong SJ. Transient lower esophageal sphincter relaxation and the related esophageal motor activities. Korean J Gastroenterol. 2012; 59:205–210.
Article
11. Sweis R, Kaufman E, Anggiansah A, et al. Post-prandial reflux suppression by a raft-forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH-impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, double-blind study in reflux patients. Aliment Pharmacol Ther. 2013; 37:1093–1102.
Full Text Links
  • KJG
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr