Korean J Dermatol.  1986 Dec;24(6):853-858.

Systemic Lupus Erythematosus Showing Vesiculobullous Eruptions: Report of Two Cases

Abstract

l6-year-old male and 48-year-old female with systemic lupus erythematosus (SLE) and renal disease presented with vesiculobullous eruptions during severe attack of the disease. They showed hypocomplementernia, and high ANA titers. Histopathologic findings revealed subepidermal blister and leukocytoclastic vasculitis, Direct immunofluorescence demonstratedlinear deposits of IgG, IgA and lgM at the dermoepidermal junction. The vesiculobullous eruption of SLE may be an important marker reflecting disease activity and prognosis.

Keyword

SLE; Renal disease; Vesiculobullous eruptions

MeSH Terms

Blister
Female
Fluorescent Antibody Technique, Direct
Humans
Immunoglobulin A
Immunoglobulin G
Lupus Erythematosus, Systemic*
Male
Middle Aged
Prognosis
Vasculitis
Immunoglobulin A
Immunoglobulin G
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