Korean J Dermatol.  1988 Jun;26(3):383-388.

Treatment of Uncomplicated Male Gonococcal Urethritis with Ceftriaxone

• Lee JT
• So SN
• Kim JH
• Kim JH

Abstract

Ceftriaxone is a new semi-synthetic, broad spectrum third generation cephalosporin. It has a high degree of stability in the presence of beta-lactamase and its half-life averages about 8 hours. A total of 109 patients with uncomplicated gonococcal urethritis seen at the VD Clinic, Choong-Ku Public Health Center, in Seoul in the periods of March April 1986, and April-May 1987, were subjected to this study. The diagnosis of gonococcal infection and the test. of cure were made on the basis of culture and Gram staining of urethral smear. The patients were divided randomly into two groups consisting of 49 and 60, and treated with ceftriaxone, 250mg, IM and 500mg, IM respectively. No failure case was seen in both groups. lt is suggested that ceftriaxone, 250mg, IM regimen may be used as the first line treatment for uncomplicated gonococcal urethritis.

Keyword

Gonococcal urethritis; Ceftriaxone

MeSH Terms

beta-Lactamases
Ceftriaxone*
Diagnosis
Half-Life
Humans
Male*
Public Health
Seoul
Urethritis*
Ceftriaxone
beta-Lactamases