Infect Chemother.  2008 Apr;40(2):67-75. 10.3947/ic.2008.40.2.67.

Recent Evidences of Sepsis Treatment

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Korea. cmcjh@catholic.ac.kr

Abstract

Severe sepsis and septic shock are conditions with a mortality rate about 50% despite of advances of antimicrobial treatment and supportive cares. Recently, investigators are trying to establish a scientific basis for identification of high-risk patients, or a standard practice for hemodynamic optimization and adjunctive pharmacologic therapies for these patients. Several randomized, controlled trials and meta-analyses about certain therapies showed significant reduction of mortality and morbidity. This article is a clinical review of contemporary management strategies recommended with evidences for severe sepsis and septic shock.

Keyword

Sepsis; Septic shock; Evidence-base medicine

MeSH Terms

Hemodynamics
Humans
Research Personnel
Sepsis
Shock, Septic
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