Korean Circ J.  1985 Jun;15(2):233-239. 10.4070/kcj.1985.15.2.233.

A Study on Relation between Carboxyhemoglobin in Smoking and Ischemic Heart Disease

• Park YH
• Park SJ
• Park EM
• Lee CK
• Hong MH

• KMID: 2229617
• DOI: http://doi.org/10.4070/kcj.1985.15.2.233

Abstract

The present study was undertaken to investigate serum carboxyhemoglobin levels in smokers according to the amount of cigarrettes. many studies have shown definite and consistent relations between smoking and ischemic heart disease. The purpose of this study is to show that COHb levels can be used to discriminate between persons having certain ischemic heart disease and persons without these disease more accurately than is possible by using smoking history alone, and thus to suggest that this may be a good indicators of risk. The results of this study are as follow : 1) The incidence of ischemic heart disease in smoker is higher than that in non-smoker. 2) For a given COHb level there is no clear increasing trend in the population of affected subjects with increasing cigarette consumption and there is no significant change cigarette consumption under duration of 10 year's smoking history. 3) For a moderate and a heavy smoking categories there is a consistent effect of an increasing proportion of affected subjects as the COHb level rises and there is a significant change with COHb level under duration of 10 year's smoking history. 4) The same results are as over duration of 10 year's history. 5) There were no significant interaction between under duration of 10 year's smoking history and over duration of 10 year's smoking history. In conclusion, it seemed that cigarette smoking may play an important factor in development of ischemic heart disease by increasing serum carboxyhemoglobin level.

MeSH Terms

Carboxyhemoglobin*
Humans
Incidence
Myocardial Ischemia*
Smoke*
Smoking*
Tobacco Products
Carboxyhemoglobin
Smoke